KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTY2D1
All Species:
16.36
Human Site:
S346
Identified Species:
30
UniProt:
Q68D10
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D10
NP_919261.2
685
75546
S346
H
K
A
K
K
S
L
S
H
P
S
H
S
R
P
Chimpanzee
Pan troglodytes
XP_508321
684
75407
S346
H
K
A
K
K
S
L
S
H
P
S
H
S
R
P
Rhesus Macaque
Macaca mulatta
XP_001082108
684
75599
S346
H
K
A
K
K
S
P
S
H
P
S
H
S
R
P
Dog
Lupus familis
XP_534086
793
86791
P457
H
K
A
K
K
S
P
P
H
P
S
H
S
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q68FG3
682
74799
S346
K
A
K
K
P
L
P
S
H
P
S
H
S
K
P
Rat
Rattus norvegicus
XP_002725626
681
74519
S346
K
A
K
K
S
L
S
S
H
P
S
H
S
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517926
644
69600
H304
P
A
A
P
S
E
K
H
T
R
P
A
T
A
K
Chicken
Gallus gallus
XP_421015
633
66869
T301
S
Q
M
E
K
G
K
T
S
Q
N
S
S
L
K
Frog
Xenopus laevis
Q6NU13
800
83727
A455
G
S
A
R
S
V
G
A
S
G
S
G
K
P
T
Zebra Danio
Brachydanio rerio
Q6DGN6
629
69420
G308
H
G
D
R
S
N
S
G
S
S
G
A
L
N
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMP6
581
65683
F267
K
Q
H
E
P
V
V
F
E
V
E
K
K
K
E
Honey Bee
Apis mellifera
XP_395689
579
67372
T265
V
P
P
P
I
D
F
T
E
L
L
K
I
A
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793115
639
72247
R299
T
G
S
N
V
P
S
R
S
I
E
K
Q
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
73.6
N.A.
80.5
82.1
N.A.
55.6
47.8
43
42.7
N.A.
28.3
23.2
N.A.
24
Protein Similarity:
100
99.5
98.5
78.8
N.A.
89.9
90.3
N.A.
66.5
58
56.6
58.6
N.A.
44.2
41.6
N.A.
39.8
P-Site Identity:
100
100
93.3
86.6
N.A.
53.3
53.3
N.A.
6.6
13.3
13.3
6.6
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
93.3
86.6
N.A.
60
60
N.A.
13.3
40
26.6
20
N.A.
26.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
47
0
0
0
0
8
0
0
0
16
0
16
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
16
0
8
0
0
16
0
16
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
8
16
0
0
0
8
8
8
0
8
8
8
0
0
0
% G
% His:
39
0
8
0
0
0
0
8
47
0
0
47
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
24
31
16
47
39
0
16
0
0
0
0
24
16
24
16
% K
% Leu:
0
0
0
0
0
16
16
0
0
8
8
0
8
16
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
8
0
0
8
8
% N
% Pro:
8
8
8
16
16
8
24
8
0
47
8
0
0
8
47
% P
% Gln:
0
16
0
0
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
0
0
16
0
0
0
8
0
8
0
0
0
31
0
% R
% Ser:
8
8
8
0
31
31
24
39
31
8
54
8
54
0
8
% S
% Thr:
8
0
0
0
0
0
0
16
8
0
0
0
8
0
8
% T
% Val:
8
0
0
0
8
16
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _